Psychoanalytic Explanation For Mood Disorders (Depression And Bipolar Disorder)

Freud's explanation of depression focuses on the idea of loss – that the root cause of all depression lies in the loss of something loved, whether it is a person or an object. Lowry (1984) added that this loss can be real or imaginary. However, some may question what separates the overwhelming sadness caused by, say, the death of a loved one, and depression? The psychoanalytic approach fails to answer this. In PJ Clayton's study, widows and widowers were studied for a year after the death of their spouses.While depression brought about by the death of a loved one is excluded as being a depressive episode by most psychologists, Clayton found that 45% of his subjects fit the criteria for diagnosis of depression. In reaction to the loss, Freud believed the depressive then develops feelings of self hatred, and begins to blame themselves for the loss. Freud also believed feelings of self hatred develop from the depressive's thoughts about unresolved conflicts which have often been repressed to the unconscious.Psychoanalytic explanations find it especially difficult to explain the cyclical nature of bipolar disorder, and mood disorders such as SAD and post natal depression; they only seem to have an explanation for depression. Melanie Klein, a post Freudian, claims that whether an individual loses his or her self esteem depends on the quality of the individual's relationship as an infant with his or her mother during the first year of life.If an individual doesn't have positive experiences with his or her mother during the first year of life, then a predisposition of depression may be planted. This also links in with the ideas of theorists such as Bowlby. There is research to back this up, linking adverse early experiences to greater likelihood of developing a mood disorder later in life e. g.Foltyn et al (1998) who found in a study of Polish medical students that 25% of examined students had depression symptoms and that these students were exposed significant ly more frequently to early negative experiences than students without depression. However, the approach has been criticised for being too deterministic. How do we explain how some individuals who have experienced trauma and separation in early childhood don't develop depression and go on to lead happy, normal lives, as shown in various case studies?Freud also believed that too many positive experiences during the first year of life (oral stage) could set an individual up for developing depression later on in life. He believed that if a child is nurtured too much – over indulged – as an infant; they could become fixated at the oral stage. The individual may develop problems later in adult life because he or she is used to receiving excessive amounts of attention as a child and perhaps not as much in adult life, so may feel rejected, unloved, and thus become depressed.A lot of the psychoanalytic explanation is very difficult to test empirically. Freud's stages of psycho sexual development occur at an unconscious level, which makes it difficult to test. Psychoanalytic explanations give insufficient weight to the role of biological factors in the development of mood disorders. The evidence regarding genetic factors, the role of neurochemicals and the effectiveness of anti-depressant drugs, appears to be ignored by psychoanalysts.A key strength to the psychoanalytic approach is that they claim their therapy targets the underlying causes of the disorder, which other treatments don't do. They claim that biological treatments, such as drugs and ECT, treat the symptoms not the underlying causes; they simply mask of disguise the underlying problems. Psychoanalytic treatments tackle those problems which are usually rooted in some significant and on going psychological problem which has its origins on early experiences – perhaps making it more effective.

Trend and effects of global immigration

Trend and Effects of Global ImmigrationImmigration is a major political issue in the United States. Elections are won or lost based on campaigners ‘ place on in-migration reform. Harmonizing to a 2008 Gallup Poll most people in the United States believe that in-migration should be decreased. ( Gallup, 2010 ) However, harmonizing to the same canvass, since 2005 Whites and inkinesss feel that in-migration should be decreased. Conversely, the information shows that Hispanics believe in-migration should be increased. In contrast, since 2005 Whites, inkinesss and Hispanics all believe that in-migration is a good thing for this state. Still, while Whites and inkinesss believe that immigrants cost revenue enhancement remunerators excessively much, yet Hispanics believe that immigrants do non be revenue enhancement remunerators excessively much. All those who responded to the Gallup Poll believe that immigrants are willing to take the low-paying occupations that Americans do n't desire ( Gallup, 2010 ) . While Gallup informations provides insight merely to tendencies in the United States, informations from the Ogranisation for Economic Co-Operation and Development ( OECD ) provides a snapshot of the world of in-migration around the universe. OECD information shows that since 2005 foreign populat ions have increased in the bulk of states tracked. The greatest additions in foreign workers are in the United States, Canada, Italy, New Zealand, and Spain ( 2009 ) .TendenciesThe migration of people is non a new phenomenon. History shows that people have migrated since antediluvian times ( Mueller, 2007 ) . â€Å" [ M ] igrations are non an stray phenomenon: motions of trade goods and capital about ever give rise to motions of people † province Castles and Miller ( as cited in Ryan, 2007 ) . The Gallup information illustrates a tendency in public sentiment in the United States that in-migration should be decreased ( 2010 ) , yet internationally, including United States, OECD information shows a tendency that existent in-migration is steadily increasing each twelvemonth ( 2009 ) . The addition in in-migration suggests another tendency in the occupation market in which low paying occupations in this state are taken by immigrants, which supports the Gallup study saying that wh ile there are many grounds for migration, the cosmopolitan desire of all is to acquire a good occupation ( Clifton, 2007 ) . Historically, immigrants were hapless males that were largely unskilled. These work forces immigrated by and large for economic grounds to direct money back to their households ( Ryan, 2007 ) . Since 1970 the profile of an immigrant has evolved to include females who choose to migrate for a assortment of grounds including household reunion, improved quality of life for their kids and good occupations ( Ryan, 2007 ; Piper, 2006 ; Horton, 2008 ; Clifton, 2007 ) . Since 1980 adult females outnumber male immigrants in states such as Australia, the United States, and Canada ( Ryan, 2007 ) .Impact of ImmigrationTo the extent that people migrate to reunite their households, acquire a good occupation, or better their fiscal state of affairs, migration is good to the person. However, the ultimate benefits of migration come at a cost. For illustration, Mexican adult females frequently migrate to supply â€Å" ideal † lives for their kids, influenced by their perceptual experiences of th e â€Å" . . . authoritative Western ideals of childhood as a infinite protected from grownup loads and the domain of monetized relationships. . . † ( Horton, 2008 ) . In their pursuits to supply perfect lives for their kids, these female parents are separated from their kids for months or even old ages at a clip in order to gain adequate money to transport their kids across boundary lines. Separations are frequently longer than expected because of increased post-9/11 boundary line enforcement. The cost for these female parents is the impairment of their relationships with their kids. To guarantee that their kids do non bury, them they send gifts to their kids such as playthings, confect and apparels. For the kids left behind the cost for them is, ironically, at the disbursal their childhoods. For illustration, eldest girls are left to â€Å" fuss † younger siblings. Children left behind sometimes feel abandoned, which fosters choler at their absent female parents. The se kids may besides endure emotionally at the abuses of schoolmates who make merriment of them because their parents have migrated to another county ( Horton, 2008 ) . Additionally, depending on how they enter a state ( i.e. , as refugees, refuge searchers, or trafficked ) and the occupations they perform ( i.e. , domestic labour, sex work, service industry work, unskilled labour ) , many adult females remain undocumented, which suggests that in-migration Numberss are even higher than reported ( Piper, 2006 ) . The economic impact of migration influences society both positively and negatively. Sending states benefit from unemployment alleviation and significant income through remittals from emigres ( Ryan, 2007 ) . Yet, directing states besides suffer from the loss of skilled workers. ( The US National Intelligence Council, 2001 ) Receiving states benefit from a new work force of skilled and unskilled labourers who fill the occupations the younger coevals come ining the work force typically does non desire. Unfortunately, employers whose concerns depend on skilled labour frequently take advantage of illegal workers with low wage, long hours, hapless conditions, and work jurisprudence misdemeanors. Yet without these workers many of these concerns would turn up. Paradoxically, as the demand for skilled workers additions, migratory workers will get down to demand higher rewards as companies compete for their accomplishments ( Hemme, 2006 ) . Harmonizing to Clifton, all states will vie for the cardinal trade good that creates occupations: encephalon addition. â€Å" Brain addition is defined as a metropolis ‘s or state ‘s attractive force of gifted people whose exceeding gifts and knowledge create new concern and new occupations and increase that metropolis ‘s or state ‘s economic system † ( 2007 ) . These human mega endowments and their supporting employees impact their local economic systems through their buying power. They besides impact their state ‘s GNP through the production of their companies ‘ goods. While states that are able to pull the mega-talents reap the ultimate economic benefits ( Gallup estimates one talented â€Å" star † per $ 100 million of GNP ) , conversely the states from which the endowment leaves suffer terrible encephalon drain through â€Å" the deficiency of skilled workers in wellness, air power, excavation, transportation and port operations † ( Clifton, 2007 ) .DecisionIn my professional experience, I have witnessed the effects of in-migration on instruction. There is enormous benefit to pupils and territories in the sharing of diverse civilizations and linguistic communications. However, increased registration of kids whose parents may non pay revenue enhancements places a important fiscal load on school territories because of the demand to engage extra instructors and supply repasts and transit. Districts realize a lessening in attending gross when migratory households return to their sending states for drawn-out periods of clip. Because of linguistic communication barriers, territories must supply more bilingual instructors, decision makers and paraprofessionals to guarantee communicating with migratory parents and pupils. Equally of import, test tonss suffer because of linguistic communication barriers and disparity in educational criterions of the sending state and having territory. Migration will go on, but the finishs chosen will finally depend on where people can â€Å" acquire a good occupation † ( Clifton, 2007 ) . Dramatic additions in in-migration are predicted in the United States, Europe, Asia and Latin America triggered by â€Å" violent struggles, economic crises, and natural catastrophes † ( The US National Intelligence Council, 2001 ) . Globalization and democratisation will do such dramatic additions hard to command. Mass migration from Mexico, Cuba and Haiti to the United States will be the consequence of poorness and political agitation ( U.S. National Intelligence Council, 2001 ) . States must mind these tendencies and anticipations, fix their substructures and develop programs to pull encephalon addition to guarantee economic success for their citizens.Mentions:Hemme, B R ( Summer 2007 ) .Global migration as a solution to worker deficits in industrialised economies.Forum on Public Policy: A Journal of the Oxford Round Table, Retri evedFebruary 23, 2010, fromAcademic OneFileviaGale: Horton, S.. ( 2008 ) . Devouring Childhood: â€Å" Lost † and â€Å" Ideal † Childhoods as a Motivation for Migration.Anthropological Quarterly,81 ( 4 ) ,925-943. Retrieved February 23, 2010, from Research Library. ( Document ID:1616811601 ) . Piper, N. ( Spring 2006 ) .Gendering the political relations of migration ( 1 ) .International Migration Review,40,1.p.133 ( 32 ) .RetrievedFebruary 23, 2010, fromAcademic OneFileviaGale: hypertext transfer protocol: //find.galegroup.com.ezproxylocal.library.nova.edu/gtx/start.do? prodId=AONE & A ; userGroupName=novaseu_main Ryan, Jan. ( 2007 ) . Globalization and migration in the twenty-first century: looking back into the hereafter. Forum on Public Policy: A Journal of the Oxford Round Table. Retrieved February 23, 2010, from Academic OneFile via Gale: hypertext transfer protocol: //find.galegroup.com.ezproxylocal.library.nova.edu/gtx/start.do? prodId=AONE & A ; userGroupName=novaseu_main The US National Intelligence Council on Turning Global Migration. ( Documents ) .Dec 2001 Population and Development Review,27,4.p.817 ( 3 ) .RetrievedFebruary 23, 2010, fromAcademic OneFileviaGale: Gallup. ( 2010 ) . Immigration. Retrieved from hypertext transfer protocol: //www.gallup.com/poll/1660/Immigration.aspx # 3

The Short Second Life of Bree Tanner Chapters 6

The room was fil ed with a sudden blaze, and I felt the warmth on my leg in the same instant that I realized there wasn't enough room for me to pin Diego to the wal without some part of myself touching the sunlight. â€Å"Bree!† he gasped. I twisted away from him automatical y, rol ing myself tight against the wal . It took less than a second, and the whole time I was waiting for the pain to get me. For the flames to hit and then spread like the night I'd met her, only faster. The dazzling flash of light was gone. It was just the pil ar of sun again. I looked at Diego's face – his eyes were wide, his mouth hanging open. He was total y stil, a sure sign of alarm. I wanted to look down at my leg, but I was afraid to see what was left. This wasn't like Jen ripping my arm off, though that had hurt more. I wasn't going to be able to fix this. Stil no pain yet. â€Å"Bree, did you see that?† I shook my head once quickly. â€Å"How bad is it?† â€Å"Bad?† â€Å"My leg,† I said through my teeth. â€Å"Just tel me what's left.† â€Å"Your leg looks fine to me.† I glanced down quickly, and sure enough, there was my foot and my calf, just like before. I wiggled my toes. Fine. â€Å"Does it hurt?† he asked. I pul ed myself off the ground, onto my knees. â€Å"Not yet.† â€Å"Did you see what happened? The light?† I shook my head. â€Å"Watch this,† he said, kneeling in front of the beam of sunshine again. â€Å"And don't shove me out of the way this time. You already proved I'm right.† He put his hand out. It was almost as hard to watch this time, even if my leg felt normal. The second his fingers entered the beam, the cave was fil ed with a mil ion bril iant rainbow reflections. It was bright as noon in a glass room – light everywhere. I flinched and then shuddered. There was sunlight all over me. â€Å"Unreal,† Diego whispered. He put the rest of his hand into the beam, and the cave somehow got even brighter. He rol ed his hand over to look at the back, then turned it palm up again. The reflections danced like he was spinning a prism. There was no smel of burning, and he clearly wasn't in pain. I looked closely at his hand, and it seemed like there were a zil ion tiny mirrors in the surface, too smal to distinguish separately, al shining back the light with double the intensity of a regular mirror. â€Å"Come here, Bree – you have to try this.† I couldn't think of a reason to refuse, and I was curious, but I was also stil reluctant as I slid to his side. â€Å"No burn?† â€Å"None. Light doesn't burn us, it just†¦ reflects off of us. I guess that's kind of an understatement.† Slow as a human, I reluctantly stretched my fingers into the light. Immediately, reflections blazed away from my skin, making the room so bright that the day outside would look dark in comparison. They weren't exactly reflections, though, because the light was bent and colored, more like crystal. I stuck my whole hand in, and the room got brighter. â€Å"Do you think Riley knows?† I whispered. â€Å"Maybe. Maybe not.† â€Å"Why wouldn't he tel us if he did? What would be the point? So we're walking disco bal s.† I shrugged. Diego laughed. â€Å"I can see where the stories come from. Imagine if you saw this when you were human. Wouldn't you think that the guy over there just burst into flames?† â€Å"If he didn't hang around to chat. Maybe.† â€Å"This is incredible,† Diego said. With one finger he traced a line across my glowing palm. Then he jumped to his feet right under the sunbeam, and the room went crazy with light. â€Å"C'mon, let's get out of here.† He reached up and pul ed himself toward the hole he'd cut to the surface. You'd think I would have been over it, but I was stil nervous to fol ow. Not wanting to seem like a total chicken, I stayed close on his heels, but I was cringing inside the whole way. Riley had real y made his point about burning in the sun; in my mind it was linked to that horrific time of burning as I became a vampire, and I couldn't escape the instinctive panic that fil ed me every time I thought of it. Then Diego was out of the hole, and I was next to him half a second later. We stood on a smal patch of wild grass, only a few feet from the trees that covered the island. Behind us, it was just a couple of yards to a low bluff, and then the water. Everything around us blazed in the color and light shining off of us. â€Å"Wow,† I muttered. Diego grinned at me, his face beautiful with light, and suddenly, with a deep lurch in my stomach, I realized that the whole BFF thing was way off the mark. For me, anyway. It was just that fast. His grin softened a little bit into just the hint of a smile. His eyes were wide like mine. Al awe and lights. He touched my face, the way he'd touched my hand, as if he was trying to understand the shine. â€Å"So pretty,† he said. He left his hand against my cheek. I'm not sure how long we stood there, smiling like total idiots, blazing away like glass torches. The inlet was empty of boats, which was probably good. No way even a mud-eyed human would have missed us. Not that they could have done anything to us, but I wasn't thirsty, and al the screaming would have ruined the mood. Eventual y a thick cloud drifted in front of the sun. Suddenly we were just us again, though stil slightly luminous. Not enough that anyone with eyes dul er than a vampire's would notice. As soon as the shine was gone, my thoughts cleared up and I could think about what was coming next. But even though Diego looked like his normal self again – not made of blazing light, anyway – I knew he would never look the same to me. That tingly sensation in the pit of my stomach was stil there. I had the feeling it might be there permanently. â€Å"Do we tel Riley? Do we think he doesn't know?† I asked. Diego sighed and dropped his hand. â€Å"I don't know. Let's think about this while we track them.† â€Å"We're going to have to be careful, tracking them in the day. We're kind of noticeable in the sunlight, you know.† He grinned. â€Å"Let's be ninjas.† I nodded. â€Å"Super-secret ninja club sounds way cooler than the whole BFF thing.† â€Å"Definitely better.† It didn't take us more than a few seconds to find the point from which the whole gang had left the island. That was the easy part. Finding where they'd touched ground on the mainland was a whole other problem. We briefly discussed splitting up, then vetoed that idea unanimously. Our logic was real y sound – after al, if one of us found something, how would we tel the other? – but mostly I just didn't want to leave him, and I could see he felt the same. Both of us had been without any kind of good companionship our whole lives, and it was just too sweet to waste a minute of it. There were so many options as to where they could have gone. To the mainland of the peninsula, or to another island, or back to the outskirts of Seattle, or north to Canada. Whenever we pul ed down or burned down one of our houses, Riley was always prepared – he always seemed to know exactly where to go next. He must have planned ahead for that stuff, but he didn't let any of us in on the plan. They could have been anywhere. Ducking in and out of the water to avoid boats and people real y slowed us down. We spent al day with no luck, but neither of us minded. We were having the most fun we'd ever had. It was such a strange day. Instead of sitting miserably in the darkness trying to tune out the mayhem and swal ow my disgust at my hiding place, I was playing ninja with my new best friend, or maybe something more. We laughed a lot while we moved through the patches of shade, throwing rocks at each other like they were Chinese stars. Then the sun set, and suddenly I was stressed. Would Riley look for us? Would he assume we were fried? Did he know better? We started moving faster. A lot faster. We'd already circled al the nearby islands, so now we concentrated on the mainland. About an hour after sundown, I caught a familiar scent, and within seconds we were on their trail. Once we found the path of the smel, it was as easy as fol owing a herd of elephants through fresh snow. We talked about what to do, more serious now as we ran. â€Å"I don't think we should tel Riley,† I said. â€Å"Let's say we spent al day in your cave before we went looking for them.† As I spoke, my paranoia started to grow. â€Å"Better yet, let's tel them your cave was fil ed with water. We couldn't even talk.† â€Å"You think Riley's a bad dude, don't you?† he asked quietly after a minute. As he spoke, he took my hand. â€Å"I don't know. But I'd rather act like he was, just in case.† I hesitated, then said, â€Å"You don't want to think he's bad.† â€Å"No,† Diego admitted. â€Å"He's kind of my friend. I mean, not like you're my friend.† He squeezed my fingers. â€Å"But more than anyone else. I don't want to think†¦Ã¢â‚¬  Diego didn't finish his sentence. I squeezed his fingers back. â€Å"Maybe he's total y decent. Our being careful doesn't change who he is.† â€Å"True. Okay, the underwater cave story it is. At least at first†¦ I could talk to him about the sun later. I'd rather do it during the day, anyway, when I can prove what I'm claiming right away. And just in case he already knows, but there's some good reason why he told us something else, I should tel him when we're alone. Grab him at dawn, when he's coming back from wherever it is he goes†¦.† I noticed a ton of I's rather than we's going on in Diego's little speech, and it bothered me. But at the same time, I didn't want much to do with educating Riley. I didn't have the same faith in him Diego did. â€Å"Ninja attack at dawn!† I said to make him laugh. It worked. We started joking again as we tracked our herd of vampires, but I could tel he was thinking serious stuff under the teasing, just like I was. And I only got more anxious as we ran. Because we were running fast, and there was no way we had the wrong trail, but it was taking too long. We were real y getting away from the coast, up and over the closest mountains, off into new territory. This wasn't the normal pattern. Every house we'd borrowed, whether it was up a mountain or on an island or hidden on a big farm, had a few things in common. The dead owners, the remote locale, and one other thing. They al were sort of focused on Seattle. Oriented around the big city like orbiting moons. Seattle was always the hub, always the target. We were out of orbit now, and it felt wrong. Maybe it meant nothing, maybe it was just that so many things were changing today. Al the truths I'd accepted had been turned upside down and I wasn't in the mood for any other upheavals. Why couldn't Riley have just picked someplace normal? â€Å"Funny they're this far out,† Diego murmured, and I could hear the edge in his voice. â€Å"Or scary,† I muttered. He squeezed my hand. â€Å"It's cool. The ninja club can handle anything.† â€Å"You got a secret handshake yet?† â€Å"Working on it,† he promised. Something started to bug me. It was like I could feel this strange blind spot – I knew there was something I wasn't seeing, but I couldn't put my finger on it. Something obvious†¦ And then, about sixty miles farther west than our usual perimeter, we found the house. It was impossible to mistake the noise. The boom boom boom of the bass, the video-game soundtrack, the snarling. Total y our crowd. I pul ed my hand free, and Diego looked at me. â€Å"Hey, I don't even know you,† I said in a joking tone. â€Å"I haven't had one conversation with you, what with al that water we sat in al day. You could be a ninja or a vampire for al I know.† He grinned. â€Å"Same goes for you, stranger.† Then low and fast, â€Å"Just do the same things you did yesterday. Tomorrow night we'l get out together. Maybe do some reconnaissance, figure out more of what's going on.† â€Å"Sounds like a plan. Mum's the word.† He ducked close and kissed me – just a peck, but right on the lips. The shock of it zinged through my whole body. Then he said, â€Å"Let's do this,† and headed down the side of the mountain toward the source of the raucous noise without looking back. Already playing the part. A little stunned, I fol owed from a few yards behind, remembering to put the distance between us that I would put between myself and anyone else.

DECISION MAKING Assignment Example | Topics and Well Written Essays - 1750 words

DECISION MAKING - Assignment Example The main challenge faced by Apple in its decision making process is regarding introduction of new products and services in the market. The premium price charged by the concerned company might create problem for its business operation in the long run. Apple Inc is well known for offering new and innovative products to its customers. The concerned company is constantly engaged in introducing unique products in the market. But the problem faced by the concerned company in delivering its new product is in determining whether the product introduced in the markets fulfils the expectations of its potential customers. The company charges high price as compared to its competitors. Therefore Apple remains in dilemma whether the consumer will consider the unique specification or feature included in the product or will compare the price while purchasing a particular product. The concerned company gained competitive advantages over its competitors in the market. Therefore in order to maintain its brand value and brand equity in the market Apple Inc is required to consider the psychological and behavioral aspects of the customers. The company is focusing only on the high end products, which might create a problem of sustainability of its business operation in long course of time. Apple is required to emphasize on introducing products both for its high end as well as low end consumers in the market. The alternatives considered for overcoming the decision making problem associated with the introduction of new product in the market is to make its premium and high-end products more attractive to its customers. The concerned company is focusing on differentiation strategy for its premium products and low cost producer which will offer an adequate product with low price. The low end product provided by the concerned company to its customers in the market should be charged below its competitor’s price. The list of resources utilized in the

The Growing Middle Class in Emerging Markets in Asia Research Paper

The Growing Middle Class in Emerging Markets in Asia - Research Paper Example This research will begin with the statement that posts 2008 financial crisis across the US and around the world, there has been considerable interest in the emergence of the Asian middle class because they can play a significant role in reviving the world economy. As more and more people in the Asian region fall into the middle-income category, they are likely to be a future growth engine. So far economies of China, South Korea, or Taiwan have been driven more by their export bases; however, with the emergence of a middle class in these countries, their reliance on exports will diminish in the coming years as their domestic consumption will fuel the future growth. It is a fact that the wider the base of a middle-income group across the world, the more cushioning will it provide to the world economy. In other words, the world economy is likely to be more resilient to the future economic shocks unlike the one witnessed during the financial crisis of 2008-09. While there is no specific definition of the middle class, different people/agencies use different criteria. According to the definition of the Asian Development Bank, the people earning between USD2 and USD20, in purchasing power parity terms, fall in a category of the middle class. According to Homi Kharas – the deputy director and the economist at the Brookings Institution, a middle class is defined as those households whose income fall between USD10 and USD100 per day based on purchasing power parity (PPP) perspective. Pezzini, the director of OECD development, argues that emerging middle class in Asian countries is likely to be a main engine of growth, especially in China and India due to their large population base. According to him, this middle class has been a front-runner in accumulating the useful capital necessary for further growth in the region. Larger middle class in the region helps fuel growth through domestic consumption rather than depending upon export-based growth. South Koreas larg e proportion of the population now falls in the middle-income category or above and has already become a major engine of economic growth in the region. Asia Foundation has been a major organization in supporting economic growth across Asia through private and public institutions. Its economic development program consists of three core areas that include policy reform and develops business environments, supporting entrepreneurship, and creating economic cooperation across the region.

Soda tax in the US Essay Example | Topics and Well Written Essays - 750 words

Soda tax in the US - Essay Example Statistics show that more than one third or 35.7% of adults in the US are obese and suffer from obesity-related conditions such as diabetes and coronary diseases. Obesity prevalence varies across different states whereby, in 2002, all states had a prevalence of more than 20% with the prevalence ranging from 34.7% in Louisiana to 20.5% in Colorado. Furthermore, the federal’s annual medical expense of obesity as of 2008 was $ 147 billion dollars (CDC, 2013). Prompted by the rise in obesity in the country, different researchers have hypothesizes different causes and suggested solutions aimed at mitigating the harmful social and economic effects of obesity. The soda tax is one such suggestion; however, not all agree on the possible benefits likely to result from the taxation of soft drinks. Whether or not adopting the soda tax in the US proves sufficient in reducing the obesity rate in the country remains a controversial issue for those for and against the tax policy. Proponents for the tax base their argument on credible research findings, which indicate that taxing soft drinks reduces high caloric intake minimizing an individual’s probability of developing obesity. First introduced as an abstract idea by the Director of Rudd Center for Food Policy and Obesity (RCFPO) Kelly D. Brownell in 1994, the soda tax aimed to improve public health while simultaneously raise revenue in the US economy. Later studies done in Yale University by the RCFPO in 2011 indicated that a penny-per-ounce levy on soft drinks would function to reduce consumption by 13%, which resulted in the elimination of 8,000 calories from a regular, American’s diet annually.... inancial implication of obesity as a reason for taxing soft drinks, which many researchers have hypothesized as one of the leading causes of obesity in the US. Revenue generated from taxing soft drinks proves beneficial for the federal and state governments whereby, governmental officials can use the funds to offset financial deficits in the budget. A survey done by the U.S Department of Health and Human Services in 2012 indicated that taxing soft drinks would generate revenue of $ 14.9 billion dollars within the first fiscal year alone (Fletcher et al, 2010). Conversely, those against the tax policy sight poor lifestyle habits such as living a sedentary life and poor nutrition (high cholesterol diet) as major causes of obesity, which if not addressed would render taxing soft drinks inefficient in minimizing the obesity rate within the country. Research done by Fletcher and colleagues in 2009 aimed at examining the impact of fluctuating soda tax in different states on body mass index (BMI) revealed that soft drinks consumption accounted for 7% of total energy intake. They concluded that if taxed at the average taxation rate of tobacco (58%) the mean BMI of the US population would only decrease by 0.16 points reducing obesity in the population by 0.7% (Fletcher et al, 2010). This showed that soft drink taxes’ influence on BMI is minimal and does little to decrease obesity in the population. Furthermore, those against this policy are of the opinion that taxation of soft drinks does not limit their accessibility because many are willing to spend more money for their preferred luxury items such as soft drinks. In conclusion, it is apparent that both the public and the government stand to benefit from the soda tax. Taxing soft drinks generates revenue for the government,

Military History Paper Research Example | Topics and Well Written Essays - 1250 words

Military History - Research Paper Example Army professional can draw from military history how areas such as casualty evacuation were managed during the Vietnam War as compared to the Civil war. Moreover, military history also enables army professionals to promote the continuity of this history by learning its value. These incentives reinforce why army professional should study military history. Introduction Winning a war requires a combination of factors, and military history is part these forces. Being in the army calls for a rich understanding of military history, which dates back to hundreds of years (Jessup, Robert, & Coakley, 2005). Today, there are few people who see the value of military history. Instead, many people believe that study of military history has no place in the current world, where war is modernized and fought using sophisticated arms. Needless to say, there are many incentives that military professional can gain through the study of military history. The United States has a collection of chronological records detailing the experiences of soldiers, war events and development of arms that add to the rich history of its military history. Overlooking these resources is not welcome, particularly when military professionals do not take time from their busy schedules to glean from these records. While many military professionals remain deployed in various hot spots, taking the time to study military history has the potential of increasing their success in war. Through the study of military history, army professionals can learn how to make appropriate decisions, manage situations in war, engage threats in war, and promote continuity of military history. Value of Military History Managing war The role of military history in teaching army professionals how to manage wars cannot be underestimated. Professional army personnel must be ready to understand how wars are managed in order to achieve defined objectives. The methodology to manage wars is an essential aspect of military history. This is because those studying military histories can see those gains made by other soldiers and reflect on them. Possibly, these army professionals can gain new insights on how war and surrounding situation can be managed to produce outcomes that align with desired objectives. For instance, there are many aspects of management that army professional can learn from history. During the Vietnam War, the United States army made significant gains by making one of the most lauded evacuation programs in military history. Military history books detail that the United States army used helicopters to conduct aeromedical evacuation that helped save the lives of many soldiers in the war. Army professionals taking military history can study this literature in depth and gain a thorough understanding of how these evacuations were possible. When studying this information, military professionals would appreciate that such services were available during the American Civil war where many solider died of their wounds (Britannica Educational Pub, 2010). Certainly, military professionals who study military history will understand the value casualty management and other facets of war. Decision making Studying military history has the potential of improving the ability of army professional to make correct decisions. Decision-making is an art that requires perfection over time. Nonetheless, reading military histo

CASE 5 Information Security and Ethics Essay Example | Topics and Well Written Essays - 1000 words

CASE 5 Information Security and Ethics - Essay Example Because it is unfortunate that a leakage of information committed by an internal employee who accesses almost every details of the valuable information daily. This issue no doubt harms the ethical bonding between the employees and the organizations. But in the case of external trespassing into the organization’s confidential information zone, the blame would directly go to its security system which basically shows the loopholes of its security protocols. But, this is another issue. The organization should make the employees of all levels signed into the document where policies have been stated transparently after distributing and describing the issues about information security. Definitely, an organization containing three employees would differ from the organization with manpower of thousand people in the sense of organizational information policy. The implementation of the e-business framework has led many organizations into serious threat about information security. From the very commencement of the internet, rather say the from the beginning the internet has came with complications and vulnerabilities that is- its basic communications as well as the nodes, norms about its protocols, authentication of its network and host frameworks etc. Dissatisfied employees, hackers, opponents and other stakeholders destroyed the internet’s vulnerabilities which caused damages of privacy, financial damages, loosing of customers, interruption in the activities and unpredictability. Many employees were allowed to access internet for authentic business purpose but actually the result went to misuse of information either from lack of compassion for uncertainty, or lack of consciousness of authentic usage of internet in the organization or exactly by the wicked intension. For these reasons, some protocols are generally set inside an org anization to make the information security system more

Research on Financial Statement Restatement and Ethics Paper

On Financial Statement Restatement and Ethics - Research Paper Example The company restated its position on august 1, 2012 stating that the financial records were not fit for their purpose in compliance with general accounting and reporting standards (Cubic Corporation, 2008). One of the impending reasons that can lead to the restatement as witnessed by the recent restatement is correcting errors. It forms one of the most common reasons for financial restatement (Cubic Corporation, 2008). It happens after the release of the financial statements. Consequently, errors are found by the company or the auditor. If the error margin is observed as material to financial statements, the statements are to be corrected and re-issued to the users. Materiality is determined if the statements will lead to the users coming to incorrect conclusions in their analysis (Taub, 2006). Another reason is the changes in GAAP. If a change in the current accounting methods brings about a change in the prior year’s statements in the case of retroactive application, the statements are required to be restated (Taub, 2005). As such, it ensures that no statement is changed over the course arises from a change in the accounting policy in use. For instance, the company chose to switch from a first-in-first-out inventory costing policy to a last-in-first-out. Consequently, the statements in the previous period must be restated in order to follow the new policy. Changes in reporting entity also cause restatement of financial statements (Lee et al., 2006). In the case of a company transition from one set of ownership to a new one or the structure of ownership change in the current year and the change has an impact in the current financial statements reporting or disclosures, the prior period comparative statements must be restated. The restatement is made to facilitate a smooth transition such that the implication will be that the change occurred in the beginning of the current year (Plumlee & Yohn, 2008b). Restatement brings about

Long Term Decisions Research Paper Example | Topics and Well Written Essays - 1000 words

Long Term Decisions - Research Paper Example This infrastructure is what fast tracts quick growth of business developments in the country and creates a workable business environment. This makes the country a good investment hub as it has the appropriate infrastructure for business development. The government’s involvement also leads to improvement in the infrastructure institutionally. This is where the government regulates performance of business to curb transaction vices such as corruption and fraud. Consumers would have to bear a heavy burden of high prices facilitated by calculated behind the scene moves by some unscrupulous traders who want fleece consumers of their hard-earned coin if price setting is left to the forces of demand and supply. The government comes in to set price controls in order to make the goods affordable to low income earners enable the manufacturers get the right return on their investment. The government’s main role is to control and maintain this balance. Other cases of government†™s involvement in the market system are the high investment projects. These are investment projects that need huge capital for them to pick up and that the country must have. The government has to take up the task since to private investors lack the financial muscle to undertake it. Such projects include electricity generation and distribution for the entire country, harbors and airports of international stature e.t.c On the other hand, government’s involvement in business is discouraged considering its drawbacks such as the cumbersome procedures encountered due to the bureaucracy in formation of the business. This leads to market inefficiencies due to the time and money wasted in boardroom meetings to come up with the right policies and structures to legitimize every business transaction such as licensing, leasing, taxation, e.t.c leading to delay in decision making thus the industry is unable to take advantage of emerging opportunities due to its rigidity. The civil serva nts who lack incentives from the government such as good salaries and allowances also lead to inefficiency in the market system. This is because they are not well motivated. Due to their low salaries, they, together with board members who are regulators of the system, engage in corruption and fraud to make an extra coin. This is common in tax officials who will opt to take huge tax bribes to wipe off a tax offender’s record instead of enforcing the set laws. Too much involvement of the government in the market system may lead to miscommunication in the industry. These is because the participants feel the government is too strict or firm thus fear to pass across information that may be vital for the smooth running and operations of businesses in the market process. This eventually leads to turbulent effects in the market such as deflation, inflation, and economic depressions. Such tides are usually very unconducive for business performance as it wrecks its environment. The USA is the leading world economy. As such, the government intervenes in the market process to ensure that this remains so and that the USA citizens enjoy the best there is to offer. The government intervenes to regulate FDI investments. This is because it wants to ensure that the country owns a major stake or controllable share in the establishment. The USA has the largest market in the world and many businesses seek to share part of it. The country has a mixed economy.

Mental Disorder Essay Example | Topics and Well Written Essays - 250 words

Mental Disorder - Essay Example Mental Disorder and Treatment Modalities Through media, the general public often conveys an image of mental disorders as patients who are unpredictable, violent, and dangerous (Flores, 2008, p. 1). However, not all mental disorders portrayed these signs and symptoms, as in the case of major depression. Major depression is a serious medical condition that affects thoughts, feelings, behavior, mood, and physical health of approximately 5-8 percent of United State’s adult population (NAMI, 2009, 3). Among all the mental disorders, major depression is the most responsive to treatment. There are three types of treatment available for depression: medication, psychotherapy, and electroconvulsive therapy (NAMI, 2009, p. 8). Psychotherapy has been shown to be effective in treating depression (NAMI, 2009, p. 11). Under this therapy is the Cognitive Behavioral Therapy (CBT). Cognitive Behavioral Therapy helps to modify the negative thinking of depressive patients by setting positive thou ghts and moods. Unlike any other method, CBT is considered to be the most rapid in producing obtained results. In fact, the average number of sessions the clients’ received is only 16 sessions.

European Terrorism in the 1970’s and 1980’s Essay Example for Free

European Terrorism in the 1970’s and 1980’s Essay In a post World War II era, terrorism and covert terrorist actions became a major weapon against the governments of many European nations. In most cases, terrorism â€Å"had two purposes: to make life unendurable for the [country], and to ensure the active support of the population by executing traitors and collaborators . † Even more, â€Å"a great number [of terrorist incidents] are directed against American targets or are related to a spillover from the problems in the Middle East . † With that said, a close look will be taken to answer three questions regarding European terrorism in the 1970’s and 1980’s which include how the European governments confronted the threat, what methods the European governments took to deal with these terrorist groups, concluding with an analysis of what motivated the terrorists. To begin with, a look will first be taken into how the European governments confronted the threat of terrorism in the 1970’s and 1980’s. The terrorist violence â€Å"during the postwar era in Europe has been characterized primarily by a combination of attacks by terrorist cells and hate crimes by individuals or small gangs of people—many of them racist skin heads . † In order to confront the terrorist actions, the European governments, for the most part, sought to compromise with a form of â€Å"conflict resolution † instead of direct action and retaliation that the United States has become so fond of employing. At first, the ideaology was to react on the defensive, without direct reaction, as it was believed that the terrorists would soon become tired of their actions and protest and the nation could move on. However, by the early 1970’s public â€Å"outrage at terrorist attacks † fueled the need for governments to act decisively in order to remove and dissemble the threat. For the first time in history, pressure was placed upon the nations that harbored and supported the terrorists . Essentially, the methods in dealing with the terrorist groups were, in the beginning, to simply let the terrorists have their say, and to attempt to negotiate, if possible. However, as the public began to find out that the heinous crimes committed on their front yards was related to terrorist actions, the European governments were forced to take direct and decisive action against the terrorists. Their methods included allocating more funds for defense and counter-terrorist measures and intelligence and to â€Å"delegitimize terrorists, to get society to see them for what they are—criminals—and to use one of [their] most important tools, the rule of law, against them . † The main defense against terrorism became the effectiveness of counter-intelligence measures and an enlightened society who no longer viewed terrorists with the pity they once deserved. The motivations of the terrorists were, at one time, honorable—as they were fighting against oppression and they didn’t employ any violent acts. However, â€Å"it will be sufficient to define political terrorism as a tactic employed by non-state actors involving the threat or use of fear-inducing forms of violence in an attempt to attain certain political objectives . † This, essentially, is terrorism in its most basic form—violence to get a fear-based reaction. However, terrorism breaks down into a much deeper psychological philosophy in which â€Å"the label of ‘terrorists’ [applies] to certain peoples struggling, by the only means within their power, to win or regain the fundamental rights recognized by the Universal Declaration of Human Rights and the United Nations Charter . † By this definition, a terrorist can be any human being facing oppression of their basic, most fundamental human rights, and is not necessarily the racially profiled stereotype that modern society has been taught to believe. Even more, throughout â€Å"history there [have] been political, social and economic situations in which endlessly and unjustly oppressed groups or races had to exercise their right to violence, their right to resist oppression by every means available . † In seeking truth and justice in their nation or culture, many terrorists choose the violent way of expressing their need for honored human rights. Moreover, â€Å"the question was not one of defending crime and violence but rather one of accepting the fact that such behavior, no matter how repugnant it appeared, had a motivation that all lovers of justice, freedom and human dignity could understand, even if they disapproved of it . † Essentially, terrorism is, as the United States public has been led to believe after the events of 9/11, the most heinous action that a human being can take in order to harm another person or nation. However, in order to understand the motivations of the terrorist, it must be recalled, and inherently understood, that they are humans too. They might be facing oppression, or they might be members of a religious cult who believe that nations who flaunt their materialism need to be punished, but the essence of the terrorist is that they are motivated by the need to fight and stand up against oppression against any odds. Overall, terrorism and covert terrorist actions have become a major weapon against the governments of many European and Western nations. Terrorism was meant to highlight the oppression that a people felt against their country, however, in many cases, terrorism evolved into brutal murders and heinous crimes. From the analysis of the three questions regarding European terrorism in the 1970’s and 1980’s, which included how the European governments confronted the threat, what methods the European governments took to deal with these terrorist groups, followed by an analysis of what motivated the terrorists, a conclusion can be drawn as to the insidious motivations of the terrorists and the evolving methods that the European governments were forced to employ to keep pace with the evolving nature of the terrorist crimes. Bibliography. Aston, Clive C. A Contemporary Crisis: Political Hostage-Taking and the Experience ofWestern Europe. Westport, CT: Greenwood Press, 1982. Crozier, Brian. The Rebels: A Study of Post-War Insurrections. Boston: Beacon Press, 1960. Martin, Gus. Understanding Terrorism: Challenges, Perspectives, and Issues. New York: Sage Publications, 2006. Oliverio, Annamarie. â€Å"US versus European Approaches to Terrorism: Size Really Does Matter. † Policing: A Journal of Policy and Practice. 2008. http://policing. oxfordjournals. org/ cgi/content/abstract/2/4/452 Schmid, Alex Peter and Ronald D. Crelinsten. Western Responses to Terrorism. London: Routledge, 1993.

Identification of Plant Material: Corallocarpus Epigaeus L

Identification of Plant Material: Corallocarpus Epigaeus L 6. MATERIALS AND METHODS 6.1 Collection The plant material was collected from the Tirupati, Andhra pradesh, India in the month of February 2014. The plant taxonomical authenticated by Prof; Dr. K. Madhava chetty, Department of Botany, SV University, Tirupati. The voucher specimen of Corallocarpus epigaeus L has been preserved in our laboratory for further collection and reference. Chemicals Various reagents like Mayer’s reagent, Wagner’s reagent, Hager’s reagent, Dragendroff’s reagent, ÃŽ ± napthol solution, Fehlings solution A B, Barfoeds reagent, Millons reagent, Ninhydrins solution, cuso4, ethanol 95%, potassium hydroxide, concentrated HNO3, pyridine, sodium nitroprusside, sodium picrate, concentrated HNO3, pyridine, sodium nitroprusside, sodium picrate, concentrated H2SO4, Glacial acetic acid, Ferric chloride, Ammonium hydroxide solution, Potassium dichromate solution, Thionyl chloride solution, Phenolpthalein, Chloroform, etc. were received from standard suppliers to Dept of Pharmacology, SIPS-Proddatur. 6.1.1 Preparation of Whole Plant ethanolic extract of Corallocarpus epigaeus L The fresh leaves of Corallocarpus epigaeus L. The sieved powder was stored in airtight container and kept at room temperature for further study. The dried powdered material (250gm) was extracted with 95% ethanol using soxhlet apparatus for about 72hours. Figure no 12: SOXHLET APPARATUS DISTILLATION APPARATUS After extraction with solvent, the marc was dried in hot air oven below 50o c and was concentrated by distilling off the solvent and evaporating to dryness. The dried extract was subjected to preliminary phytochemical screening for detection of various phytoconstituents. 6.1.2 Qualitative Phytochemical Analysis74 The ethanolic extract Corallocarpus epigaeus L was subjected to various analytical tests in order to identify various phytoconstituents. Test for Alkaloids Mayer’s test To 1 ml of the extract, a drop or two drop of Mayer’s reagent was added by the side of test tube. Appearance of a white or creamy precipitate indicates presence of alkaloids. Wagner’s Test To 1 ml of the extract, few drops of Wagner’s reagent was added. Development of reddish brown colour indicates the presence of alkaloids. Hager’s Test To the 1 ml of the extract, few drops of Hager’s reagent was added. A prominent yellow colour indicates the test as positive. Dragendroff’s Test To the 1 ml of the extract, few drop of Dragendroff’s reagent was added. A prominent yellow colour indicates the test as positive. Test for Carbohydrates Benedict’s Test To 5 ml of Benedict’s reagent, 1 ml of the extract solution was added and boiled for 2 minute and cooled. Formation of red precipitate shows the presence of carbohydrates. Molisch’s Test To 2 ml of extract, two drops of alcoholic solution of ÃŽ ±-naphthol was added and shaken well. Later 1 ml of concentrated sulphuric acid was added slowly along the side of the test tubes and allowed to stand. A violet ring indicates the presence of carbohydrates. Fehling’s Test To 1 ml of the extract, add equal quantity of Fehling solution A and B were added. Appearance of red precipitate indicates the presence of sugars. Barfoed’s Test To 2 ml of the extract, 2 ml of Barfoed reagent was added and mixed well. It was heated for 1-2 minute in boiling water bath and cooled. Formation of red precipitate Indicates the presence of sugars. Test for Protein and Amino Acids Million’s Test To 2 ml of the extract, few drops of Million reagent was added. A white precipitate Indicates the presence of proteins. Ninhydrin Test To the 2 ml of the extract, two drops of Ninhydrin solution was added. A characteristic purple color indicates the presence of amino acids, proteins and peptides. Biurett Test To 1 ml of the extract, one or two drop of 1% copper sulphate solution was added and tothis 1 ml of ethanol (95%) was added, followed by excess of potassium hydroxide pellets. The pink layer in ethanolic layer indicates the presence of proteins. Xanthoprotein Test To 1 ml of the extract, add 1 ml of concentrated Nitric acid was added resulting in the formation of a white precipitate which is then boiled and cooled. Then 20% sodium hydroxide in ammonia was added. Orange colour indicates the presence of aromatic amino acids. Test for Glycosides Legal’s Test 2 ml of extract was dissolved in the solution of pyridine. Then sodium nitroprusside was added, to make it alkaline. The change in the colour from yellow to orange was not observed, which indicates the presence of glycosides. Baljet’s Test To 1 ml of the extract, 1 ml of sodium picrate solution was added. The colour from yellow to orange reveals the presence of glycosides. Borntrager’s Test To 1 ml of extract, few ml of sulphuric acid was added, boiled, filtered and extracted with chloroform. The chloroform layer was than treated with few ml of ammonia. The formation of red colour indicates the presence shows the presence of anthraquinone glycosides. Keller Killani Test The extract was dissolved in acetic acid containing traces of ferric chloride and was transferred to a test tube containing sulphuric acid. At the junction, the formation of reddish brown colour, which gradually turns to blue, confirms the presence of glycosides. Test for Flavonoids Shinoda Test To 1 ml of extract, magnesium turnings was added and 1-2 drops of concentrated hydrochloric acid was added drop wise. Formation of pink to crimson colour indicates the presence of flavonoids. Alkaline reagent Test The aqueous solution of the extract was treated with 10% ammonium hydroxide solution. Yellow fluorescence indicates the presence of flavonoids. Tests for Tannins and Phenolic compounds Ferric chloride Test To 1 ml of the extract, add few drops of neutral 5% ferric chloride solution. Formation of dark greenish colour shows the presence of phenolic compounds. To the extract add potassium dichromate solution, formation of a precipitate shows the presence of tannins and phenolic compounds. Test for Triterpenoids Two or three granules of tin metal were added to thionyl chloride solution present in a test tube. Later 1 ml of extract solution was added. The formation of pink colour indicates the presence of triterpenoids. Test for Saponins The 1 ml of the extract was diluted with distilled water and the volume was made up to 20 ml. The suspension was shaken in a graduated cylinder for 15 minutes. Appearance of foam indicates the presence of saponins. Tests for Fixed Oil Spot test A small quantity of the extract was pressed between two filter papers. Appearance of oily stain on the presence of fixed oils. Saponification Test A few drops of 0.5 N alcoholic potassium hydroxide solution was added to a small quantity of extract along with a drop of phenolphthalein. The mixture was heated on water bath for 2 hrs. Formation of the soap or partial neutralization of alkali indicates the presence of fixed oil. Tests for Steroids Libermann Buchard Test 1ml of the extract was dissolved in 2 ml of chloroform in a dry test tube. 10 drops of acetic anhydride and 2 drops of concentrated sulphuric acid was added to it. The solution turns to red, then blue and finally bluish green, indicating the presence of steroids. Salkowski Test The extract was dissolved in chloroform the extract in chloroform and equal volume of concentrated sulphuric acid was added. Formation of bluish red to cherry red colour in chloroform layer and green fluorescence observed acid indicates the presence of steroids. 6.2 INVITRO ANTICANCER ACTIVITY Cell Lines COLO 320 cell lineswere obtained from sugen Life Sciences Pvt. Ltd., Tirupati and cultured in RPMI 1640 medium (Difco, invitrogen corp, Canada). General information74 Organism Homo sapiens, human Tissue Colon Product Format Frozen Morphology Cells are rounded and refractile Culture Properties Loosely adherent, multicell aggregates Biosafety Level 1 Disease DukestypeC,colorectaladenocarcinomas Age 55 years Gender Female Ethnicity Caucasian Storage Condition Liquid nitrogen vapor phase GenesExpressed Serotonin,norepinephrine,epinephrine,Adreno Cortico Tropic Hormone (ACTH), parathyroid hormone. Tumorigenic effectsYes, in nude mice CommentsCells are weakly positive for keratins Culture Method The base medium for this cell line is formulated RPMI-1640 Medium. 6.2.1 Tryphan Blue dye Exclusion Assay Method75 Table 5: List of instruments Table 6: List of Chemicals Experimental Design The designed study consists of three groups viz: Negitive control, Control, Test. In the Negative control group the cell lines were incubated with the medium for a period of 24 hours. This group was designed to rule out the possibility of any growth inhibitory effect of certain compounds of medium. The control group was designed to rule out the effect of any residual or traces of solvent with which the extract was prepared on the growth inhibition of cell lines. Here the solvent employed was ethanol and hence it is added at the concentration of 0.1% (v/v) in distilled water. In test group different concentrations of test extract i.e, 10, 25, 50, 75 and 100 µg/ml are incubated with colo 320 cell lines for a period of 24 hours. This group was used to study the effect on cell line viability. Table7: Experimental Design to Study the Effect of Ethanolic Extract of Corallocarpus epigaeus L on colo 320 Cell Line Viability by Tryphan Blue Assay Procedure 1. An aliquot of cell suspension being tested for viability was centrifuged for 5 min andsupernatant was discarded. The size of the aliquot depends on the approximate number of cells present. The aliquot is taken such that it contained a convenient number of cells to count in a haemocytometer when suspended in 1 ml PBS and then diluted again by mixing with 0.4% Tryphan blue (e.g., 5 Ãâ€"105 cells/ml). 2. The cell pellet was resuspended in 1 ml PBS or serum free complete medium. Serum proteins stain with Tryphan blue and can produce misleading results. Hence determinations must be made in serum-free solution. 3. Mix 1 part of 0.4% Tryphan blue and 1 part cell suspension (dilution of cells) cells were mixed and allowed to incubate at room temperature for approximately 3 minutes, Cells were counted within 3 to 5 min of mixing with Tryphan blue, as longer incubation periods will lead to cell death and reduced viability counts. Mixing was performed in a well of a microtiter plate or a small plastic tube using 10 to20  µl each of cell suspension and Tryphan blue. 4. A drop of the Tryphan blue/cell mixture was applied on to haemocytometer. The haemocytometer on the stage of a binocular microscope and cells were focused clearly. 5. The no. of unstained (viable) and stained (nonviable) cells were counted separately in the haemocytometer. Seeding of Cells COLO 320 cells were cultured to reach the 80-90% confluency using RPMI 1640 medium. After reaching the desired confluency, culture was collected and centrifuged at 3000 rpm for 10 minutes to get cell pellet. The pellet was resuspended in 1ml of fresh culture media. Cell concentration was determined by Tryphan blue assay was performed by mixing 50  µlitres of culture and 50  µlitres of 0.4% tryphan blue dye. Finally cells seeded in 24 well plates at the concentration 10000 cells/ml and incubated at 5% co2 incubator at 370 c for 24 hours. Drug Treatment Cells were maintained in 24 well plates in triplicate for every concentration, and treated with different concentrations of (10, 25, 50, 75, 100 µgm). Corallocarpus epigaeus L, test compound and control groups were treated with medium and ethanol. The treated cells were incubated for 24 hours in 5% co2 incubator at 370c. Invitro Cytotoxic Assay After 24 hours incubation the cells were collected from each well in eppendroffs and centrifuged at 3000rpm for 10 min to get cell pellet, to the pellet 50 µlit of each medium and tryphan blue was added and mixed well to suspend the pellet. Cytotoxicity was screened by performing tryphan blue assay. Percent of growth inhibition was calculated by using the following formula 6.2.2 Micro Culture Tetrazolium Assay76 Plant Material Used: Whole plant ethanolic extract of Corallocarpus epigaeus L. Principle This assay is based on the capacity of mitochondria succinate dehydrogenase enzymes in living cells to reduce the yellow coloured watersolublesubstrate3(4,5dimethylthiazolyl)2,5diphenyltetrazoliumbromideintoaninsolublepurplecolouredformazanproductwhosecolouredismeasuredbymeansofELISAreaderat540nm.Onlyviablecellswithactivemitochondria reducesignificant amountsof MTT, since reduction of MTT can only occur in metabolically active cells. Figure 13: Reduction of MTT to a formazan compound by mitochondrial Enzymes Cell Lines Human colorectal adenocarcinoma- colo 320were obtained by sugen Life Sciences Pvt. Ltd., Tirupati from an authenticated supplier. Stock culture of these cell lines were cultured in RPMI -1640 with 10% inactivated newborn bovine serum, Penicillin (100 IU/ml), Streptomycin (100 µg/ml)) under humidified. The cells were dissociated in 0.2% trypsin and 0.02% EDTA in phosphate buffered saline solution. The stock culture was grown in 25cm 2 tissue culture flasks and cytotoxicity experiments were carried out in 96 well microtiter plates. Procedure Cell lines in the exponential growth phase were selected, washed, trypsinized and suspended in complete culture media i.e, RPMI 1640. The microtiter plates and incubated for 24hrs during which a partial monolayer was formed. They were then exposed to various concentrations of the extract (1-100 µg/ml). Control wells received only the maintenance medium. The plates were incubated at 37 °C and 48 hrs and cells were periodically checked for granularity, shrinkage and swelling. After 48 hrs, the sample solution in wells was flicked off and 50 µl of MTT dye was added to each well. The plates were gently shaken and incubated for 4 hrs at 370C in 5%CO2 incubator. The supernatant was removed and 50  µl of DMSO was added. The plates were gently shaken to solubilise the formed formazan. The absorbance was measured at 540nm. The percentage of growth inhibition was calculated using the following formula, Values of absorbance were converted into percentage of residual viability. Usually the Inhibition concentration 50% (IC50) is chosen as the best biological marker of cytotoxicity. The IC50 value represents the concentration of the test extracts that reduced 50% of cell inhibition. Statistical analysis Statistical evaluation of data was done by one-way analysis of variance (ANOVA) followed by Tukey’s multiple comparison test on viability using computer based fitting program (Prism graph pad prism version 6.03) statistical significance was set at p,0.05. IC50 was calculated by linear interpolation method using the formula IC50 = Ãâ€"(D-C)+C Where A = The first point on the curve, expressed in percent inhibition, that is less than 50% B = The first point on the curve, expressed in percent inhibition, that is greater than or equal to 50% C = The concentration of inhibitor that gives A% inhibition D = The concentration of inhibitor that gives B % inhibition

Importance of Community Sports Programmes

Importance of Community Sports Programmes Hemel Hempstead INTRODUCTION The lack of a sports programme in our community has left many young people with no choice but to rely toon gadgets for entertainment and to pass time. Therefore, I feel strongly that theres a need for us to try and save our young generation from the world of new technology that has taken the whole world by storm. We need to go back to those days where the only way to entertain yourself was through activities, e.g. playing games, dramas, socializingsocialsing and so forth. DISCUSSION Today in our community, young people have lost the practicality of what life is. Many of the youths have become too lazy, they cant even use their brains to do anything involving or rather challenging instead they rely on apps to do everything. Many of these young people are now doing verymuch less in terms of socializingsocialising and helping their parents doing choruschores at home. Above all their health is at high risk because they are not doing anything to keep them physically fit. I argue that council representatives need to recreate sports programmes in our community as soon as possible.as thisthes programmes will boost theiryoung people participation in sport that can generate a variety of economic benefits. Sports in the community can, and does do, have positive impacts on individuals, especially young people in the communities and wider society. Below is the research on how sports have impacted on our economy, health and culture. Economic impact In 2010, sport and sport-related activity contributed  £20.3 billion to the English economy 1.9% of the England total. The contribution to employment is even greater sport and sport-related activity is estimated to support over 400,000 full-time equivalent jobs, 2.3% of all jobs in England. Health impact Physical activity, including sport, is linked to reduced risk of over 20 illnesses, including diseases such as cancers Taking part in regular sport can save between  £1,750 and  £6,900 in healthcare costs per person. Social and cultural impact Published studies show the positive effects of sport on education include improved attainment, lower absenteeism and drop-out, and increased progression to higher education. For instance, young peoples participation in sport improves their numeracy scores by 8 per cent on average above non-participants. Sport programmes can help youths who are at risk of criminal behaviour to enhance self-esteem and reduce reoffending. Benefits of sport | Sport England https://www.sportengland.org/research/benefits-of-sport/ Published studies show the positive effects of sport on education include improved attainment,lower absenteeism and drop-out, and increased progression to higher education. For instance,young peoples participation in sport improves their numeracy scores by 8 per cent on average above non-participants.   CONCLUSION Sport(s) is something all can bond over, despite the differences in social or economic circles. You dont Besides, you dont have to be rich, well educated, or come from a good home to enjoy sports. All walks of life find themselves staring at the television rooting onfor their favourite team. All fans, no matter their background, want(s) to be in the stands during an exciting game and they dont care if they are sitting next to someone of the same social standing as they are, so long as they are a rabid fan rooting for their team, of course. For a moment, at least, there is no worry about who has more than whom. There is no comparison, Thanks to sports that makes us all equal. http://www.artsite.tv/impact-of-sport-on-human-society/ Sports is something all can bond over, despite the differences in social or economic circles. You dont have to be rich, well educated, or come from a good home to enjoy sports. You dont have to be refined or crass to be a rabid spectator. All walks of life find themselves staring at the television rooting on their favorite team. All fans, no matter their background, wants to be in the stands during an exciting game and they dont care if they are sitting next to someone of the same social standing as they are, so long as they are a rabid fan rooting for their team, of course. For a moment, at least, there is no worry about who has more than whom. There is no comparison, no socio-economic struggle. There is just a group of people enjoying a game.

An Analysis of Extraordinary Little Cough :: Extraordinary Little Cough

An Analysis of Extraordinary Little Cough    The text written by Dylan Thomas is an interesting semi-autobiographical one, that may seem to be a simple piece of prose at a first glance,   but goes a lot deeper,   by playing with the language,   and cultural peculiarities.   Ã‚  Ã‚  Ã‚  Ã‚   One of the things that distinguishes this text from a lot of his others,   is the fact that it is partially written in a narrative form.   The author takes two roles in this piece of prose.   Some of the time he takes on the role of a narrator,   and is telling the story,   as if he were telling the reader about something that happened to him as a child. "As I bent down,   three lumps of sugar fell from my blazer pocket." However,   in other parts of the story,   he also takes on the part of a character in the book.   Then he slips out of his role as narrator,   and takes over the character of   the boy who can't seem to handle girls in a way,   that would make him very popular with them. "You've got a beautiful name." Another thing that makes this passage so interesting is the fact that the author uses a semi-colon instead of a full-stop in his sentences.   This gives the text a certain amount of continuity,   and thus makes it more enjoyable to read. " Their arms and legs and throats were brown as berries;   I could see that when they laughed their teeth were white;   they stepped onto the beach (...)" The exception to this,   are the monologues between the various characters (especially between a boy and a girl).   Here the sentences on the whole,   seem to be very short,   sharp,   and almost comical.   Dylan Thomas does this to emphasise the insecurity between the different sexes,   and to bring out the idea that we are reading about children in puberty,   where they are confronted with many problems,   such as discovering the opposite sex. "oh!   it's just ordinary." "Shall I see you again?" "If you want to."    These short sentences are also to be seen in line twenty,   where the author leaves a sentence all by itself on that line.   Short sentences,   like in the dialogues help to emphasise the awkwardness between boy and girl at this age,   and underline the style used in the dialogues between the two sexes.    "The cap dropped at her feet"

Coming of Age in A Tree Grows in Brooklyn :: Tree Grows in Brooklyn Essays

Coming of Age in A Tree Grows in Brooklyn Betty Smith's A Tree Grows in Brooklyn presents the problems of a child growing up, the coming of age when one meets challenges and overcomes obstacles. The protagonist, Francie Nolan, undergoes a self-discovery as she strives to mature living in the Brooklyn slum despite its poverty and privation. Thus, Smith's thematic treatment of the struggle of maturity has become for the reader an exploration of loneliness, family relationships, the loss of innocence, and death and disease. One of the challenges of growing up is loneliness. As a small child living in Brooklyn Francie had no friends her age, the kids in her neighborhood that would have been candidates for friends either found her too quiet or shunned her for being different. Betty Smith describes on page 106 how most of Francie's childhood days were spent: "So in the warm summer days the lonesome child sat on her stoop and pretended disdain for the group of children playing on the sidewalk. Francie played with her imaginary companions and made believe they were better than real children. But all the while her heart beat in rhythm to the poignant sadness of the song the children sang while walking around in a ring with hands joined." As time went by and Francie got older she began to get to know a different kind of loneliness. Betty Smith narrates her feelings on page 403: "Spring came early that year and the sweet warm nights made her restless. She walked up and down the streets and through t he park. And wherever she went, she saw a boy and a girl together; walking arm-in-arm, sitting on a park bench with their arms around each other, standing closely and in silence in a vestibule. Everyone in the world but Francie had a sweetheart or a friend she seemed to be the only lonely one in Brooklyn without a friend." Loneliness is one of the challenges we must all conquer as part of maturing and it helps us learn to be independent and overcome hardship. Family relationships are a second problem faced by all in their coming of age. Francie loves her Johnny Nolan, her father, more than anything, she adores the way he talks and the way that he sings.

First day in college Essay

Most people’s first day at college is the most stressful day of their lives because they don’t know what to expect or they just don’t want to go through an embarrassing situation, but for me it was the most exciting day of my life. First, I met new people who shared my interests, second it was a whole new experience for me in which success depended on me, and third it was the first day that I started studying something that I really liked. Finally I won’t forget it very easily because lots of things were accomplished in my first day at UNACH. First I met lots of people who were as excited as me for their first day at college. I really enjoyed that day because everybody I talked to were people who were going to study English with me, so we shared the same interest. My new friends and I talked a lot that day about the first things that crossed our minds, and then we exchanged our emails. In my case I tried to look for the people who where completely interested in the program, the ones that were 100% of what they were doing and that they were not going to drop out the program in afew months. Second, for me it was an amazing experience that I had never gone through in my life. For the first time in my entire life I was studying something that I was really into of. Studying English for me was the best choice because I knew that I was meant to study languages. The other new thing is that succeeding depended exclusively on me; nobody was going to be pushing me to study or to prepare my homework. This new stage in my life was totally new for me and it was something that I had to get used to. Third, it was the first day I started studying something that I really liked, I have always liked languages not just English, But I always said to myself that the first one that I was going to learn world be English. Although I didn’t speak much English I remember that in my first day I tried to practice my English as much as possible, but it was difficult to find the person who dared to speak English. After some unsuccesful tries I found the person who took the risk and she didn’t care about others, she was Leticia. I know that we made lots of mistakes but we didn’t care, we just did our best and were able to understand each other, which was the point. Finally, I won’t forget that day because it was one of the most special moments of my life. That day I received more things of what I had expected, I got friends, I was the first day of my English program, I realized that there was something that I was really good at. Now that I am in my third year and I look back and I see that it was the best choice I have ever made, I have no regrets, these last three years have been the most remarkable and greatest years of my life.

Administrative Law Rev Essay

Freedom of Information Act 1982 is entirely in the interest of public who can have access to various documents of government of Victoria and its public agencies for verification or for any other useful purpose.   The sole objective of FOI Act is to bring awareness among public whether the functioning and operations of government are in order   and how public analyze the same. Section 22 provides about the charges to be paid for having access to specific documents.   The section provides technical details of payment of fee that is calculated with time that is taken for search of documents.   This is particularly due to the fact that   the time taken for search of documents may vary depending on the date of publication of document. This is also in order to reduce the payment of fee to be paid by public.   All sectors of public may not afford to pay high rate of fees for having access to government documents.   In view of such as these reasons, hourly rate and time taken for search of documents has been included in this section. The section also covers transcription (h)   and routine requests (g)   and in case of inspection of documents no charge shall be calculated (f) in pursuance of Section 8(1) or 11(1). Section 27 clearly states about reasons of refusal of documents by a Minister of state to that effect, applicant shall be informed about the reasons in writing.   This section is somewhat complicated with the fact that a minister or a government official is a servant of public and with that motive, public must be provided access to the documents which is the sole purpose of FOI Act. This section is likely to give rise to conflicts between and may bring a deep dissatisfaction to public. Some of the documents that contain health information are also restricted with the provisions of Health   Records Act 2001, which of these reasons are also to be stated to applicant.   Although there are clauses for applying of review of decisions, launch complain to Ombudsmen, it is both time consuming and   undecisive for applicants to move further with such grievances. Section 50 deals with applications for review which would be pending with Tribunal for decisions.   This may pertain to a request for document, charge made, decision for access, or any other specific request regarding information under FOI Act.  Ã‚  Ã‚   The Tribunal in all respects has to deal with each individual case, giving its due importance of provisions along with genuine reasons. This section is in favor of public, as Tribunal shall reconsiders and reviews the decisions and grants permissions to public in various aspects that are relevant to FOI Act. The Tribunal may refuse the decision of Minister or agency and give an order in favor of public. Those issues or requests for documents which were not considered by Minister, are very well resolved at Tribunal by applicants. Section 51 states that an applicant may apply to Principal officer or Minister for review of decision, which was given in the deemed absence within 28 days   for review of decision or refusing to give access to health documents as per Section 36 of Health Records Act 2001. This section offers powers and opportunities to public   for   reconsideration of requests for having access to documents.   Applicants have to be excessively vigilant in deriving the maximum benefit from the government bodies and officials.  Ã‚  Ã‚   This section is both useful for public and for principal officers to check the veracity of facts in all respects. Section 51A  Ã‚  Ã‚   deals with conciliation of Health Service Commissioner   which state that issues that were deferring in Section 50 and 51 in the matters of health documents, may suitably be taken up by applicant with this section and apply for Health Service Commissioner’s decision.   In case Health Service Commissioner fails to conciliate a request, to that effect an notice in writing must be issued to both applicant and Principal Officer. This appears as a last resort for applicant as the decision of Health Service Commissioner is the final approach for an applicant. Conclusion The enactment of FOI is made with a view of regularizing the functioning and to increase the   working efficiency of governments.   Apart from this fact, the public are also provided an in-depth knowledge about information and working status of governments. Although there are many technicalities involved in FOI Act, each section, sub-section and clause, a significance of reason is attached to it for the benefit of both public and governing bodies.

Digestion: Describe the digestion of a burger Essay

Digestion A burger is broken down mechanically by biting into it. The food in the mouth sets off salivary glands that secrete salivary amylase, which breaks down amylase in the burger. When the food is broken down enough, the tongue shapes the food in a bolus, or a ball. The bolus is pushed back to the pharynx at the back of the throat. The food stimulates the opening of the flap so the good goes down the esophagus, rather than the windpipe. Because of peristalsis, rhythmic waves created by muscles in the throat, the food slides easily down the digestive tract. Salivary amylase continues to break down the starch all the way down the esophagus. When the burger reaches the stomach, the epithelium, or stomach wall, secretes gastric juice which has a very high concentration of hydrochloric acid and breaks up the burger. In the gastric juice is also an enzyme that hydrolyzes proteins called pepsin. This pepsin starts out as the inactive pepsinogen, and is activated by hydrochloric acid in the epithelium. After this, the burger is churned in the stomach and becomes chyme, or vomit. From the stomach, the burger goes through the pyloric sphincter and into the small intestine. In the first 25 cm of the small intestine, the food goes through the duodenum, a place where pancreatic enzymes and bile from the live are stored. Bile, along with the enzyme lipase, breaks down fat while the enzyme nuclease breaks down nucleic acids and various enzymes, such as trypsins and peptidases, break down the proteins. These substances are called by hormones which act based on stimuli received, such as the food in the duodenum. Absorption also occurs in the small intestine because of its large surface area. It has a very large surface area because villi, or finger like projections on the surface, contain microvilli, smaller projections on the surface of the villi. Because of this, the surface area of the small intestine is greatly increased. The large intestine, or colon, has the job of retaining water. It reabsorbs water and nutrients that remain in the lumen. The undigested materials are then excreted in feces, and the digestion of the burger is completed.

Microelectronics Reliability Essay

Abstraction Micro-Electro-Mechanical Systems or short MEMS, is a engineering that is basically a combination of electro-mechanical stuffs and mechanical technology at a micro graduated table. The engineering used for fiction is derived from the IC fiction procedures and typically ranges from one micrometer to several millimetres. The MEMS engineering finds its usage in assorted applications where for case, micro detectors and/or micro actuators are needed. As its name suggests, MEMS devices are basically mechanical devices that can dwell of fixed parts or a combination of fixed and traveling parts. However this besides gives rise to dependability issues due to both electrical as mechanical issues [ 2 ] s.a. stuff weariness, stiction, dazes etc. The dependability can be greatly enhanced [ 1 ] turn outing the engineering can be suited for usage in high terminal applications. The end of this essay is to present and familiarise the reader to an extent with the operation and the dependability issues of a MEMS accelerometer. First the working of a MEMS accelerometer will be covered after which its dependability will be considered. Here assorted dependability issues will be considered after which†¦Ã¢â‚¬ ¦..some†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.solutions will be given on how to cover with†¦..some†¦..of†¦..the dependability issues. Finally a decision will be drawn if the presented solution†¦Ã¢â‚¬ ¦.solutions†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..are bettering the dependability.IntroductionMEMS engineering devices have established a repute over the old ages as capable detector and actuator devices doing assorted information garnering techniques possible. The engineering enables applications to garner information from the environment in assorted spheres merely to change over them to the electrical sphere. Following to the electrical sphere, the detectors can be fabricated to observe mechanical, thermic, chemical, magnetic and optical signals. †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ Give some more illustrations about the usage and demo some images etc. particularly mention the usage in automotive industry †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ One noteworthy illustration that possibly talk easy to the head is the usage of MEMS detectors in the modern smartphones. The detector enables the phone to observe up from down for assorted maps s.a. exchanging to a larger screen, GPS applications and game characteristics where the phone detects the tilting for playing some games. Figure†¦ ..shows the usage of accelerometers germinating over the old ages. [ 4 ] As the figure points out, the MEMS accelerometer had made its first visual aspect as a clang detector in an airbag. From there it evolved to be used even in playthings where it needs to be inexpensive and is produced in a high volume. However an application in toys doesn’t need to be extremely dependable unlike the usage in application for automotive terminals s.a. the airbag where a life can be saved depending on the right operation of the detector.1. MEMS accelerometerBasic operationFigures†¦shows a basic MEMS capacitive accelerometer. [ 4 ] †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ . The MEMS detector shown uses two home bases connected to the cardinal mass w.r.t the fixed home bases as differential capacitances. The electrical capacity is given by The two home bases attached to the cardinal mass signifier series electrical capacities with the fixed home bases. When there is acceleration the mass will travel in the positive or negative way depending on the motion. This in bend will ensue in positive or negative electrical capacity and depending on the distance the capacitances are smaller or larger. Thus for positive motion one capacitance will increase positively while the other will increase negatively, or frailty versa for negative motion. When there is no acceleration the movable mass will be back at its place due to the snap belongingss of Si which consequences in a place equidistance between each outer plates. This will ensue in zero electromotive force on the cardinal home base as the electrical capacity on each side are equal ( except for the sine ) . This is because the outer home bases can be driven with a square moving ridge with the coveted frequence so that one home base sees a positive signal while the other sees a negative signal, and frailty versa. For positive motion the end product square moving ridge is in stage with the input signal resulting in a greater magnitude when demodulated. For negative motion this is the antonym. The described device has merely two outer home bases which means that the sensitiveness will be low. To increase the sensitiveness the figure off traveling fingers ( outer plates ) must be increased [ 1 ] . However every bit will be shown in the text, the more moving parts in the accelerometer the higher the chance of failure.2. Common MEMS failure mechanismsAlthough the MEMS engineering has proved its worth, there are many failure mechanisms that need to be considered when planing to hold a qualitative merchandise at the terminal of the processing. Table†¦ [ 6 ] summarizes the common failure mechanisms of MEMS devices:FailureCauseMechanical FractureOverload, daze ; Corrosion ; FatigueStictionVan der Waals force ; Capillary force ; Chemical bonding ; Electrostatic charging ; Residual emphasisCharge accretionElectric emphasis ; Radiation ; Improper handlingWearAdhesion ; Abrasion ; Corrosion ; Surface wearinessCreep and wearinessIntrinsic emphasis ; Applied emphasis ; Thermal emphasisElectric short and unfastenedDielectric stuff debasement ; ESD, high electric field ; Electromigration ; OxidationContaminationIntrinsic ( e.g. , crystal growing ) ; Manufacturing-induced ; Usage enviro nment-inducedAs the accelerometer is considered as the instance survey, merely some of the failure mechanisms are of involvement. The most of import failure mechanisms are Mechanical breaks. Following to that stiction is besides of import as the accelerometer contains traveling parts. In ulterior subdivisions some solutions will be presented on how to better some of the failure mechanisms.Mechanical fractures†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Mechanical break is the most common failure manner and largely is a consequence of Shocks. Dazes are fundamentally sudden accelerations. While usually an accelerometer operates under conditions merely holding to cover low g-shocks s.a. in consumer electronics, auto clang detectors need to defy much more than that to be dependable. Apart from dazes the mechanical failure manner can besides be a consequence of in-use-stiction as a consequence of suspended parts doing contact that under normal conditions doesn’t occur. The latter will be shows in the fol lowing subdivision.Reducing mechanical breaksTo better the MEMS accelerometer assorted methods can be used. One normally used method is to restrict the motion of the cogent evidence mass by implementing a stopper. Figure†¦..shows an execution of the latter. [ 7 ] The T-shaped construction is the stopper. By implementing the stopper, the break of the back uping beams can be avoided as the maximal emphasis on the beams given by the snap is non exceeded. Following to restricting the emphasis it besides prevents the in-use-stiction as the moving parts are prevented from doing contact with the fixed parts. †¦Ã¢â‚¬ ¦..fatigue†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..shocks†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦..StictionStiction is one of the most common failure mechanisms in MEMS and occurs where suspended constructions are used ( traveling parts ) . When different parts s.a. the fixed fingers in the accelerometer make contact, these can stay affiliated to one another. Figure†¦Ã¢â‚¬ ¦ . [ 6 ] †¦shows some illustrations of sidelong or/and perpendicular stiction. Fig†¦ Examples of assorted stiction ( a ) no stiction ; ( B ) merely sidelong stiction ; and ( degree Celsius ) lateral and perpendicular stiction [ 6 ] . The stiction occurs peculiarly in micromachined constructions where the surface country to volume ratio is big ensuing in a typically little stiffness of reconstructing springs. The stiction can hold assorted causes and most of these can be due to processing, elevated RH degrees and dazes. The adhesion occurs either due to van der Waals, electrostatic forces ( trapped charge ) , capillary forces or a combination of these [ 7 ] .Reducing stictionAs the failure mechanisms of MEMS devices are progressively researched, many ways have been proposed to cut down stiction. Some of these where:Modifying the structural stiffnessDesign of the traveling parts with higher stiffness to get the better of the stiction forceSurface chemical scienceUsing hydrophobic surfaces to forestall H2O from coming into contact with the MEMS structures as H2O causes capillary force and hence stiction [ 6 ] . Alternatively a hermetic waterproofing can be usedRough surfacesRough surfaces reduces the Van der Waals f orce and with that the stictionImplementing a stopper to restrict the motion of the cogent evidence mass ( see old subdivision )Anti stiction coating3. DependabilityDefinition of the dependabilityBefore discoursing the dependability of an accelerometer, the definition of dependability must be considered. Reliability is defined as the chance of a certain merchandise to execute harmonizing to its specifications within typical operating conditions for the expected life-time [ 2 ] . The expression for this is given by As for the failure rate, which is defined as the ratio of the entire figure of failures to the entire operating clip [ 1 ] . Thus ? For measuring the dependability there are several standard theoretical accounts that can be used, viz.The exponential dependability distributionThe binomial dependability distributionThe Poisson dependability distributionWeibull dependability distributionIn this text the exponential signifier is used for the dependability analysis as its less complex than other lifetime distribution theoretical accounts. Then the dependability is given by In world the failure rate is besides a map of clip. The failure rate ( as a map of clip ) follows the behaviour of a bathing tub curve [ 1 ] . [ 2 ] The infant mortality part is caused by merchandise defects and perchance besides by cognize how restrictions like when proving paradigms [ 2 ] , as for the wear-out part, this is merely as its name suggests. Here the chance of no failure before clip T is given by [ 9 ] When ciphering the failure rate for increasing smaller intervals of clip, the jeopardy rate H ( T ) is obtained, with However, because we are sing the exponential failure distribution, the jeopardy rate will be changeless and equal to the failure rate. Here we can see merely the utile clip from the bathing tub curve, that is, most infant mortality failures ( with ruinous defects ) can be filtered out during fabricating trials [ 1 ] . This means that we can see the failure rate to be more changeless and therefore the instantaneous jeopardy rate H ( T ) is merely the failure rate.4. Dependability of a capacitive accelerometerAs was stated in the Introduction subdivision, the capacitive accelerometer will be used for the chance analysis since it’s widely used and needs to be dependable adequate particularly in life endangering state of affairss s.a. auto clangs. The structural diagram of an accelerometer with 2N-fingers is shown in Figure†¦ . [ 8 ] Here the accelerometer consists of fixed and movable parts which all demand to be fault-free. The accelerometer consists of 4 ground tackles, 4 back uping beams, 2N-fixed fingers, one movable cardinal mass and N-movable fingers attached to the cardinal mass. As stated before, utilizing more fingers increases the sensitiveness of the accelerometer. Here the system can be considered as a series theoretical account [ 1 ] because if any of the constituents fail, the whole system fails. For simpleness, the fixed parts can be considered holding perfect dependability as most defects are filtered out during the fabricating trial while the traveling parts can hold a higher dependability of failure. The dependability is so given by ( Rdegree Fahrenheitcorresponds to the traveling fingers ) Therefore the entire failure rate is merely the amount of the failure rates which is given by As can be noted, there is a trade-off between the sensitiveness and the failure rate as both are dependent on n-fingers. As the figure of fingers can be increased to better the sensitiveness, this will convey the dependability down.5. General solutionAs discussed antecedently the mechanical break and stiction are thermoset of import failure mechanisms. Here it was shows how to cut down these failures and hence besides the dependability. However if the device fails anyway so it’s considered useless. Unfortunately this can hold serious effects if it’s used in airbag systems and therefore the dependability still needs to be higher. To make this a more general attack can be used. This attack makes usage of ‘spare parts’ . If the accelerometer is broken up into smaller faculties connected together with some excess faculties, the latter can be used to replace the faulty faculties. As the faculties can be connected to some circuitry that would feel if the moving parts are faulty, a faulty faculty can be excluded and replaced by a excess one and this procedure is repeated until the redundant parts are used for replacing. This method is known as BISR ( built in self fix ) . Figure†¦..illustrates this. †¦ . Here the k-out-of-n redundancy theoretical account can be used for the analysis [ 1 ] . The k-out-of-n system consists out of n-modules, withK-modules non-faulty to guarantee the right operation of the MEMS system. When utilizing such a system, until all the excess faculties are used and at least one faculty from the chief device is faulty at the clip, so the system can no longer map decently. This means that the system, unlike when merely one chief faculty is used, is a parallel system. Figure†¦.illustrates this. †¦.. As the figure shows a 3-out-4 system is assumed. Notice that merely the moving parts are considered. That’s similar to the one-module device we can concentrate on the moving parts merely as these cut down the dependability at higher rate than the fixed parts. Again the dependability of one faculty can be done similar as for the one faculty device antecedently discussed in text. The dependability is so given by ( Rdegree Fahrenheitcorresponds to the traveling fingers ) Therefore the entire failure rate is merely the amount of the failure rates which is given by Notice that unlike earlier, the failure rate is reduced as the figure of traveling fingers are increased for better sensitiveness. This means that the trade-off that had to be made earlier is non made any more and a much better dependability is obtained. The entire dependability of a system is given [ 1 ] by Where m is the excess faculty. Therefore in this instance the dependability is given by Inserting the exponential signifier of the dependability for a faculty However, utilizing this method besides increases the usage of the figure of back uping beams which in bend reduces the dependability. But in the visible radiation of the improved dependability by utilizing the BISR attack, the overall dependability increases more than is decreases [ 1 ] doing this method really utile.DecisionMEMS have proven to be rather utile. However like any merchandise dependability issues can originate. The dependability of MEMS in toys doesn’t need to be all that high while for applications in automotive this needs to be really dependable as a unrecorded can depend on it when used in airbag systems. It has been shown that first it’s best to see the failure mechanisms and to better these which makes a longer lifetime possible. To better the dependability even further the BISR attack can be considered. From this it shows that the dependability can be really high and in the hereafter this attack might be considered to better other types of MEMS detectors.Mentions[ 1 ] X. Xiong, Y. Wu, and W. Jone, â€Å"Reliability analysis of self-repairable MEMS accelerometer, † in Proceedings of the 21st IEEE International Symposium on Defect and Fault Tolerance in VLSI Systems ( DFT '06 ) , pp. 236–244, October 2006 [ 2 ] Jacopo Iannacci, â€Å"Reliability of MEMS: A position on failure mechanisms, betterment solutions and best patterns at development level† , Center for Materials and Microsystems – CMM, Fondazione Bruno Kessler – FBK, Via Sommarive, 18, 38123 Povo, Trento, Italy, accepted 2014 [ 3 ] Frank CHoLLET, Haobing LIUâ€Å"A ( non so ) short direction to MEMS† , Creative Commons, version 5.1, 2013 [ 4 ] Michael Kraft, Neil M. White â€Å"MEMS for automotive and aerospace applications† , Woodhead Publishing Limited, Cambridge, 2013 [ 5 ] X. Xiong, Y. Wu, and W. Jone, â€Å"Material weariness and dependability of MEMS accelerometers, † in Proceedings of the 23rd IEEE International Symposium on Defect and Fault Tolerance in VLSI Systems ( DFT '08 ) , pp. 314–322, October 2008 [ 6 ] Ynhan Huang et Al. â€Å"MEMS Reliability Review† , IEEE TRANSACTIONS ON DEVICE AND MATERIALS RELIABILITY, VOL. 12, NO. 2, JUNE 2012 [ 7 ] Allyson L. Hartzell, et Al. â€Å"MEMS Reliability† , Springer, New York, 2011 [ 8 ] hypertext transfer protocol: //www.fandroides.com/wp-content/uploads/2014/04/8930-62341-How-does-smart-phone-accelerometer-work.png [ 9 ] hypertext transfer protocol: //en.wikipedia.org/wiki/Failure_rate